Molecular Mechanisms of Class B GPCR Activation: Insights from Adrenomedullin Receptors

[Image: see text] Adrenomedullin (AM) is a 52 amino acid peptide that plays a regulatory role in the vasculature. Receptors for AM comprise the class B G protein-coupled receptor, the calcitonin-like receptor (CLR), in complex with one of three receptor activity-modifying proteins (RAMPs). The C-ter...

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Publicat a:ACS Pharmacol Transl Sci
Autors principals: Garelja, Michael L., Au, Maggie, Brimble, Margaret A., Gingell, Joseph J., Hendrikse, Erica R., Lovell, Annie, Prodan, Nicole, Sexton, Patrick M., Siow, Andrew, Walker, Christopher S., Watkins, Harriet A., Williams, Geoffrey M., Wootten, Denise, Yang, Sung H., Harris, Paul W. R., Hay, Debbie L.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2020
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7155197/
https://ncbi.nlm.nih.gov/pubmed/32296766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.9b00083
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