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Perspective: Implications of Ligand–Receptor Binding Kinetics for Therapeutic Targeting of G Protein-Coupled Receptors
[Image: see text] The concept of ligand–receptor binding kinetics has been broadly applied in drug development pipelines focusing on G protein-coupled receptors (GPCRs). The ligand residence time (RT) for a receptor describes how long a ligand–receptor complex exists, and is defined as the reciproca...
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| 出版年: | ACS Pharmacol Transl Sci |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Chemical Society
2020
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| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7155193/ https://ncbi.nlm.nih.gov/pubmed/32296761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.0c00012 |
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