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Gold‐Catalyzed Atroposelective Synthesis of 1,1′‐Binaphthalene‐2,3′‐diols

A highly atroposelective (up to 97 % ee) Au‐catalyzed synthesis of 1,1′‐binaphthalene‐2,3′‐diols is reported starting from a range of substituted benzyl alkynones. Essential for the achievement of high enantioselectivity during the key assembly of the naphto‐3‐ol unit is the use of TADDOL‐derived α‐...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Zhang, Jianwei, Simon, Martin, Golz, Christopher, Alcarazo, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7155015/
https://ncbi.nlm.nih.gov/pubmed/31859408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201915456
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