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Transduction optimization of AAV vectors for human gene therapy of glaucoma and their reversed cell entry characteristics
The trabecular meshwork (TM) of the eye is responsible for maintaining physiological intraocular pressure (IOP). Dysfunction of this tissue results in elevated IOP, subsequent optic nerve damage and glaucoma, the world’s leading cause of irreversible blindness. IOP regulation by delivering candidate...
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| Udgivet i: | Gene Ther |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7153980/ https://ncbi.nlm.nih.gov/pubmed/31611639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41434-019-0105-4 |
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