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Deciphering the transcriptomic landscape of tumor-infiltrating CD8 lymphocytes in B16 melanoma tumors with single-cell RNA-Seq

Recent studies have proposed that tumor-specific tumor-infiltrating CD8(+) T lymphocytes (CD8 TIL) can be classified into two main groups: “exhausted” TILs, characterized by high expression of the inhibitory receptors PD-1 and TIM-3 and lack of transcription factor 1 (Tcf1); and “memory-like” TILs,...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Carmona, Santiago J., Siddiqui, Imran, Bilous, Mariia, Held, Werner, Gfeller, David
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7153840/
https://ncbi.nlm.nih.gov/pubmed/32313720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1737369
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