Landscape mapping of shared antigenic epitopes and their cognate TCRs of tumor-infiltrating T lymphocytes in melanoma

HLA-restricted T cell responses can induce antitumor effects in cancer patients. Previous human T cell research has largely focused on the few HLA alleles prevalent in a subset of ethnic groups. Here, using a panel of newly developed peptide-exchangeable peptide/HLA multimers and artificial antigen-...

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Библиографические подробности
Опубликовано в: :eLife
Главные авторы: Murata, Kenji, Nakatsugawa, Munehide, Rahman, Muhammed A, Nguyen, Linh T, Millar, Douglas G, Mulder, David T, Sugata, Kenji, Saijo, Hiroshi, Matsunaga, Yukiko, Kagoya, Yuki, Guo, Tingxi, Anczurowski, Mark, Wang, Chung-Hsi, Burt, Brian D, Ly, Dalam, Saso, Kayoko, Easson, Alexandra, Goldstein, David P, Reedijk, Michael, Ghazarian, Danny, Pugh, Trevor J, Butler, Marcus O, Mak, Tak W, Ohashi, Pamela S, Hirano, Naoto
Формат: Artigo
Язык:Inglês
Опубликовано: eLife Sciences Publications, Ltd 2020
Предметы:
Immunology and Inflammation
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7234812/
https://ncbi.nlm.nih.gov/pubmed/32314731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.53244
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