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PAC proton-activated chloride channel contributes to acid-induced cell death in primary rat cortical neurons

Severe local acidosis causes tissue damage and pain, and is associated with many diseases, including cerebral and cardiac ischemia, cancer, infection, and inflammation. However, the molecular mechanisms of the cellular response to extracellular acidic environment are not fully understood. We recentl...

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Bibliografske podrobnosti
izdano v:Channels (Austin)
Main Authors: Osei-Owusu, James, Yang, Junhua, Del Carmen Vitery, Maria, Tian, Mengnan, Qiu, Zhaozhu
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7153786/
https://ncbi.nlm.nih.gov/pubmed/32093550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2020.1730019
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