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PAC proton-activated chloride channel contributes to acid-induced cell death in primary rat cortical neurons

Severe local acidosis causes tissue damage and pain, and is associated with many diseases, including cerebral and cardiac ischemia, cancer, infection, and inflammation. However, the molecular mechanisms of the cellular response to extracellular acidic environment are not fully understood. We recentl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Channels (Austin)
Hauptverfasser: Osei-Owusu, James, Yang, Junhua, Del Carmen Vitery, Maria, Tian, Mengnan, Qiu, Zhaozhu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7153786/
https://ncbi.nlm.nih.gov/pubmed/32093550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2020.1730019
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