Nalaganje...

PAC, an evolutionarily conserved membrane protein, is a proton-activated chloride channel

Severe local acidosis causes tissue damage and pain, and is one of the hallmarks of many diseases including ischemia, cancer, and inflammation. However, the molecular mechanisms of the cellular response to acid are not fully understood. We performed an unbiased RNA interference screen and identified...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Science
Main Authors: Yang, Junhua, Chen, Jianan, del Carmen Vitery, Maria, Osei-Owusu, James, Chu, Jiachen, Yu, Haiyang, Sun, Shuying, Qiu, Zhaozhu
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305803/
https://ncbi.nlm.nih.gov/pubmed/31023925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aav9739
Oznake: Označite
Brez oznak, prvi označite!