A Markov model of glycosylation elucidates isozyme specificity and glycosyltransferase interactions for glycoengineering

Glycosylated biopharmaceuticals are important in the global pharmaceutical market. Despite the importance of their glycan structures, our limited knowledge of the glycosylation machinery still hinders controllability of this critical quality attribute. To facilitate discovery of glycosyltransferase...

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Udgivet i:Curr Res Biotechnol
Main Authors: Liang, Chenguang, Chiang, Austin W.T., Hansen, Anders H., Arnsdorf, Johnny, Schoffelen, Sanne, Sorrentino, James T., Kellman, Benjamin P., Bao, Bokan, Voldborg, Bjørn G., Lewis, Nathan E.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7153765/
https://ncbi.nlm.nih.gov/pubmed/32285041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.crbiot.2020.01.001
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