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Predictive glycoengineering of biosimilars using a Markov chain glycosylation model
Biosimilar drugs must closely resemble the pharmacological attributes of innovator products to ensure safety and efficacy to obtain regulatory approval. Glycosylation is one critical quality attribute that must be matched, but it is inherently difficult to control due to the complexity of its biogen...
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| Publicado no: | Biotechnol J |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5293603/ https://ncbi.nlm.nih.gov/pubmed/27860290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/biot.201600489 |
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