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Modulating carbohydrate-protein interactions through glycoengineering of monoclonal antibodies to impact cancer physiology
Diverse glycans on proteins help impact cell and organism physiology along with drug activity. Since many protein-based biotherapeutics are glycosylated and these glycans have biological activity, there is a desire to engineer glycosylation for recombinant protein-based biotherapeutics. Engineered g...
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| Publicado no: | Curr Opin Struct Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5161599/ https://ncbi.nlm.nih.gov/pubmed/27639240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2016.08.008 |
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