Загрузка...
Evaluation of Quantitative Relationship Between Target Expression and Antibody-Drug Conjugate Exposure Inside Cancer Cells
Antibody-drug conjugates (ADCs) employ overexpressed cell surface antigens to deliver cytotoxic payloads inside cancer cells. However, the relationship between target expression and ADC efficacy remains ambiguous. In this manuscript, we have addressed a part of this ambiguity by quantitatively inves...
Сохранить в:
| Опубликовано в: : | Drug Metab Dispos |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The American Society for Pharmacology and Experimental Therapeutics
2020
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7153564/ https://ncbi.nlm.nih.gov/pubmed/32086295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.119.089276 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|