Acetate as a model for aspartate-based CXCR4 chemokine receptor binding of cobalt and nickel complexes of cross-bridged tetraazamacrocycles

A number of disease states including WHIM syndrome, HIV infection and cancer have been linked to the chemokine receptor CXCR4. High-affinity CXCR4 antagonist transition metal complexes of configurationally restricted bis-tetraazamacrocyclic ligands have been identified in previous studies. Recently...

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Udgivet i:Dalton Trans
Main Authors: Cain, Amy N., Freeman, TaRynn N. Carder, Roewe, Kimberly D., Cockriel, David L., Hasley, Travis R., Maples, Randall D., Allbritton, Elisabeth M. A., D’Huys, Thomas, van Loy, Tom, Burke, Benjamin P., Prior, Timothy J., Schols, Dominique, Archibald, Stephen J., Hubin, Timothy J.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7153303/
https://ncbi.nlm.nih.gov/pubmed/30729243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8dt04728f
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