Calpain-2 activity promotes aberrant endoplasmic reticulum stress-related apoptosis in hepatocytes

BACKGROUND: Calpain-2 is a Ca(2+)-dependent cysteine protease, and high calpain-2 activity can enhance apoptosis mediated by multiple triggers. AIM: To investigate whether calpain-2 can modulate aberrant endoplasmic reticulum (ER) stress-related apoptosis in rat hepatocyte BRL-3A cells. METHODS: BRL...

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Detalles Bibliográficos
Publicado en:World J Gastroenterol
Main Authors: Xie, Ru-Jia, Hu, Xiao-Xia, Zheng, Lu, Cai, Shuang, Chen, Yu-Si, Yang, Yi, Yang, Ting, Han, Bing, Yang, Qin
Formato: Artigo
Idioma:Inglês
Publicado: Baishideng Publishing Group Inc 2020
Assuntos:
Basic Study
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7152521/
https://ncbi.nlm.nih.gov/pubmed/32308346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v26.i13.1450
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