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Suberoylanilide hydroxamic acid upregulates histone acetylation and activates endoplasmic reticulum stress to induce apoptosis in HepG2 liver cancer cells

Suberoylanilide hydroxamic acid (SAHA) is a histone deacetylase inhibitor that has demonstrated clinical activity against various solid tumors. The aim of the present study was to explore the effects of SAHA on the apoptosis of HepG2 liver cancer cells, as well as the potential mechanisms involved i...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Yu, Lei, Xie, Rujia, Tian, Tian, Zheng, Lu, Tang, Lei, Cai, Shuang, Ma, Zihua, Yang, Ting, Han, Bing, Yang, Qin
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732958/
https://ncbi.nlm.nih.gov/pubmed/31516571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10705
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