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In vitro evolution of herpes simplex virus 1 (HSV-1) reveals selection for syncytia and other minor variants in cell culture

The large dsDNA virus herpes simplex virus 1 (HSV-1) is considered to be genetically stable, yet it can rapidly evolve in response to strong selective pressures such as antiviral treatment. Deep sequencing has revealed that clinical and laboratory isolates of this virus exist as populations that con...

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Detalhes bibliográficos
Publicado no:Virus Evol
Main Authors: Kuny, Chad V, Bowen, Christopher D, Renner, Daniel W, Johnston, Christine M, Szpara, Moriah L
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7151645/
https://ncbi.nlm.nih.gov/pubmed/32296542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ve/veaa013
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