Differentiated Human SH-SY5Y Cells Provide a Reductionist Model of Herpes Simplex Virus 1 Neurotropism

Neuron-virus interactions that occur during herpes simplex virus (HSV) infection are not fully understood. Neurons are the site of lifelong latency and are a crucial target for long-term suppressive therapy or viral clearance. A reproducible neuronal model of human origin would facilitate studies of...

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Bibliographic Details
Published in:J Virol
Main Authors: Shipley, Mackenzie M., Mangold, Colleen A., Kuny, Chad V., Szpara, Moriah L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686721/
https://ncbi.nlm.nih.gov/pubmed/28956768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00958-17
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