PERK-Mediated Unfolded Protein Response Signaling Restricts Replication of the Tick-Borne Flavivirus Langat Virus

The unfolded protein response (UPR) maintains protein-folding homeostasis in the endoplasmic reticulum (ER) and has been implicated as both beneficial and detrimental to flavivirus infection. Protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK), a sensor of the UPR, is commonly associated...

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Bibliographic Details
Published in:Viruses
Main Authors: Lewy, Tyler G., Offerdahl, Danielle K., Grabowski, Jeffrey M., Kellman, Eliza, Mlera, Luwanika, Chiramel, Abhilash, Bloom, Marshall E.
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7150897/
https://ncbi.nlm.nih.gov/pubmed/32197325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12030328
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