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Tick-Borne Flaviviruses Depress AKT Activity during Acute Infection by Modulating AKT1/2

Tick-borne flaviviruses (TBFVs) are reemerging public health threats. To develop therapeutics against these pathogens, increased understanding of their interactions with the mammalian host is required. The PI3K-AKT pathway has been implicated in TBFV persistence, but its role during acute virus infe...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Kirsch, Joshua M., Mlera, Luwanika, Offerdahl, Danielle K., VanSickle, Marthe, Bloom, Marshall E.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598186/
https://ncbi.nlm.nih.gov/pubmed/32977414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12101059
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