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Structural and Functional Characterization of the Bestrophin-2 Anion Channel
The bestrophin family of calcium (Ca(2+))-activated chloride (Cl(−)) channels, which mediate the influx and efflux of monovalent anions in response to the levels of intracellular Ca(2+), comprises four members in mammals (Best1-4). Here we report cryo-EM structures of bovine Best2 (bBest2) bound and...
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| Publicado en: | Nat Struct Mol Biol |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7150642/ https://ncbi.nlm.nih.gov/pubmed/32251414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-0402-z |
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