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Targeting Proteasomal Degradation of Soluble, Misfolded Proteins: Ubi Major…
This chapter deals with small molecule modulators of the ubiquitin–proteasome system (UPS). They are designed to restore its impaired capacity to dispose of soluble, dysfunctional protein copies, and to fight its pathological impairment in proteinopathies in general and in tauopathies in particular....
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| Publicado en: | Chemical Modulators of Protein Misfolding and Neurodegenerative Disease |
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| Autor Principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7150093/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-801944-3.00003-5 |
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