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To misfold or to lose structure?: Detection and degradation of oxidized proteins by the 20S proteasome

Aggregation of proteins damaged by stress is often a causal factor of cell death. To prevent aggregation, eukaryotic cells rapidly degrade damaged proteins by engaging two types of proteasomes. The first type is the 26S proteasome (26SP) which is composed of a cylindrical proteolytic core—the 20S pr...

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Detalhes bibliográficos
Principais autores: Kurepa, Jasmina, Smalle, Jan A
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634309/
https://ncbi.nlm.nih.gov/pubmed/19704573
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