Aggravated brain injury after neonatal hypoxic ischemia in microglia-depleted mice

BACKGROUND: Neuroinflammation plays an important role in neonatal hypoxic-ischemic encephalopathy (HIE). Although microglia are largely responsible for injury-induced inflammatory response, they play beneficial roles in both normal and disease states. However, the effects of microglial depletion on...

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Publicado en:J Neuroinflammation
Autores principales: Tsuji, Shunichiro, Di Martino, Elena, Mukai, Takeo, Tsuji, Shoko, Murakami, Takashi, Harris, Robert A., Blomgren, Klas, Åden, Ulrika
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7149909/
https://ncbi.nlm.nih.gov/pubmed/32276642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01792-7
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