Microglia depletion aggravates the severity of acute and chronic seizures in mice

Microglia are the resident immune cells of the center nervous system and participate in various neurological diseases. Here we determined the function of microglia in epileptogenesis using microglial ablation approaches. Three different microglia-specific genetic tools were used, CX3CR1(CreER/+):R26...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Brain Behav Immun
Main Authors: Wu, Wenning, Li, Yujiao, Wei, Yujia, Bosco, Dale B., Xie, Manling, Zhao, Ming-Gao, Richardson, Jason R., Wu, Long-Jun
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572576/
https://ncbi.nlm.nih.gov/pubmed/32621847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2020.06.028
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