Human IgA Monoclonal Antibodies That Neutralize Poliovirus, Produced by Hybridomas and Recombinant Expression

Poliovirus (PV)-specific intestinal IgAs are important for cessation of PV shedding in the gastrointestinal tract following an acute infection with wild type or vaccine-derived PV strains. We sought to produce IgA monoclonal antibodies (mAbs) with PV neutralizing activity. We first performed de novo...

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Publicado en:Antibodies (Basel)
Autores principales: Puligedda, Rama Devudu, Vigdorovich, Vladimir, Kouiavskaia, Diana, Kattala, Chandana Devi, Zhao, Jiang-yang, Al-Saleem, Fetweh H., Chumakov, Konstantin, Sather, D. Noah, Dessain, Scott K.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7148538/
https://ncbi.nlm.nih.gov/pubmed/32121092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antib9010005
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