Membrane-bound and soluble forms of an NMDA receptor extracellular domain retain epitopes targeted in auto-immune encephalitis

BACKGROUND: Anti-NMDA receptor encephalitis (ANRE) is a potentially lethal disease attributed to auto-antibodies against the N-methyl-D-aspartate receptor (NMDAR). Full recovery is possible if therapy is initiated early in the disease course. Detection of ANRE antibodies in the cerebrospinal fluid (...

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Veröffentlicht in:BMC Biotechnol
Hauptverfasser: Sharma, Rashmi, Al-Saleem, Fetweh H., Puligedda, Rama Devudu, Rattelle, Amy, Lynch, David R., Dessain, Scott K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Methodology Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6020338/
https://ncbi.nlm.nih.gov/pubmed/29945600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-018-0450-1
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