Alcohol Metabolizing Enzymes, Microsomal Ethanol Oxidizing System, Cytochrome P450 2E1, Catalase, and Aldehyde Dehydrogenase in Alcohol-Associated Liver Disease

Once ingested, most of the alcohol is metabolized in the liver by alcohol dehydrogenase to acetaldehyde. Two additional pathways of acetaldehyde generation are by microsomal ethanol oxidizing system (cytochrome P450 2E1) and catalase. Acetaldehyde can form adducts which can interfere with cellular f...

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Bibliografische gegevens
Gepubliceerd in:Biomedicines
Hoofdauteurs: Jiang, Yanchao, Zhang, Ting, Kusumanchi, Praveen, Han, Sen, Yang, Zhihong, Liangpunsakul, Suthat
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
Onderwerpen:
Review
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7148483/
https://ncbi.nlm.nih.gov/pubmed/32143280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8030050
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