Association between Aldehyde Dehydrogenase 2 Glu504Lys Polymorphism and Alcoholic Liver Disease

BACKGROUND: Only a subset of patients with excessive alcohol use develop alcoholic liver disease (ALD); though the exact mechanism is not completely understood. Once ingested, alcohol is metabolized by 2 key oxidative enzymes, alcohol (ADH) and aldehyde dehydrogenase (ALDH). There are 2 major ALDH i...

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Veröffentlicht in:Am J Med Sci
Hauptverfasser: Chang, Binxia, Hao, Shuli, Zhang, Longyu, Gao, Miaomiao, Sun, Ying, Huang, Ang, Teng, Guangju, Li, Baosen, Crabb, David W., Kusumanchi, Praveen, Wang, Li, Liangpunsakul, Suthat, Zou, Zhengsheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063768/
https://ncbi.nlm.nih.gov/pubmed/29779728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.amjms.2018.03.012
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