Alcohol Metabolizing Enzymes, Microsomal Ethanol Oxidizing System, Cytochrome P450 2E1, Catalase, and Aldehyde Dehydrogenase in Alcohol-Associated Liver Disease

Once ingested, most of the alcohol is metabolized in the liver by alcohol dehydrogenase to acetaldehyde. Two additional pathways of acetaldehyde generation are by microsomal ethanol oxidizing system (cytochrome P450 2E1) and catalase. Acetaldehyde can form adducts which can interfere with cellular f...

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Bibliographic Details
Published in:Biomedicines
Main Authors: Jiang, Yanchao, Zhang, Ting, Kusumanchi, Praveen, Han, Sen, Yang, Zhihong, Liangpunsakul, Suthat
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7148483/
https://ncbi.nlm.nih.gov/pubmed/32143280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8030050
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