Skip is essential for Notch signaling to induce Sox2 in cerebral arteriovenous malformations

Notch signaling and Sry-box (Sox) family transcriptional factors both play critical roles in endothelial cell (EC) differentiation in vascularization. Recent studies have shown that excessive Notch signaling induces Sox2 to cause cerebral arteriovenous malformations (AVMs). Here, we examine human pu...

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Publicado en:Cell Signal
Main Authors: Zhang, Daoqin, Qiao, Xiaojing, Wang, Lumin, Zhang, Li, Yao, Jiayi, Wu, Xiuju, Yu, Tongtong, Boström, Kristina I., Yao, Yucheng
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7147809/
https://ncbi.nlm.nih.gov/pubmed/31927035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2020.109537
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