Crosstalk between BMP and Notch Induces Sox2 in Cerebral Endothelial Cells

Bone morphogenetic protein (BMP) and Notch signaling are critical for endothelial cell (EC) differentiation in vascular development. Recent studies have shown that excess BMP activity induces Notch signaling in cerebral ECs resulting in arteriovenous malformation (AVMs). However, it is unclear how t...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Wu, Xiuju, Yao, Jiayi, Wang, Lumin, Zhang, Daoqin, Zhang, Li, Reynolds, Eric X., Yu, Tongtong, Boström, Kristina I., Yao, Yucheng
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628192/
https://ncbi.nlm.nih.gov/pubmed/31174355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8060549
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