Crosstalk between BMP and Notch Induces Sox2 in Cerebral Endothelial Cells

Bone morphogenetic protein (BMP) and Notch signaling are critical for endothelial cell (EC) differentiation in vascular development. Recent studies have shown that excess BMP activity induces Notch signaling in cerebral ECs resulting in arteriovenous malformation (AVMs). However, it is unclear how t...

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Vydáno v:Cells
Hlavní autoři: Wu, Xiuju, Yao, Jiayi, Wang, Lumin, Zhang, Daoqin, Zhang, Li, Reynolds, Eric X., Yu, Tongtong, Boström, Kristina I., Yao, Yucheng
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628192/
https://ncbi.nlm.nih.gov/pubmed/31174355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8060549
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