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Crosstalk between BMP and Notch Induces Sox2 in Cerebral Endothelial Cells

Bone morphogenetic protein (BMP) and Notch signaling are critical for endothelial cell (EC) differentiation in vascular development. Recent studies have shown that excess BMP activity induces Notch signaling in cerebral ECs resulting in arteriovenous malformation (AVMs). However, it is unclear how t...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cells
Hauptverfasser: Wu, Xiuju, Yao, Jiayi, Wang, Lumin, Zhang, Daoqin, Zhang, Li, Reynolds, Eric X., Yu, Tongtong, Boström, Kristina I., Yao, Yucheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628192/
https://ncbi.nlm.nih.gov/pubmed/31174355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8060549
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