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Does breast carcinoma belong to the Lynch syndrome tumor spectrum? – Somatic mutational profiles vs. ovarian and colorectal carcinomas

Inherited DNA mismatch repair (MMR) defects cause predisposition to colorectal, endometrial, ovarian, and other cancers occurring in Lynch syndrome (LS). It is unsettled whether breast carcinoma belongs to the LS tumor spectrum. We approached this question through somatic mutational analysis of brea...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Porkka, Noora K., Olkinuora, Alisa, Kuopio, Teijo, Ahtiainen, Maarit, Eldfors, Samuli, Almusa, Henrikki, Mecklin, Jukka-Pekka, Peltomäki, Päivi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7147090/
https://ncbi.nlm.nih.gov/pubmed/32292574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27538
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