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Does breast carcinoma belong to the Lynch syndrome tumor spectrum? – Somatic mutational profiles vs. ovarian and colorectal carcinomas

Inherited DNA mismatch repair (MMR) defects cause predisposition to colorectal, endometrial, ovarian, and other cancers occurring in Lynch syndrome (LS). It is unsettled whether breast carcinoma belongs to the LS tumor spectrum. We approached this question through somatic mutational analysis of brea...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Porkka, Noora K., Olkinuora, Alisa, Kuopio, Teijo, Ahtiainen, Maarit, Eldfors, Samuli, Almusa, Henrikki, Mecklin, Jukka-Pekka, Peltomäki, Päivi
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7147090/
https://ncbi.nlm.nih.gov/pubmed/32292574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27538
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