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Breast cancer bone metastases are attenuated in a Tgif1-deficient bone microenvironment
BACKGROUND: Osteoclast activation is a hallmark of breast cancer-induced bone disease while little is known about the role of osteoblasts in this process. Recently, we identified the homeodomain protein TG-interacting factor-1 (Tgif1) as a crucial regulator of osteoblast function. In this study, we...
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| Publicado no: | Breast Cancer Res |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7146874/ https://ncbi.nlm.nih.gov/pubmed/32272947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-020-01269-8 |
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