Neuronal BIN1 Regulates Presynaptic Neurotransmitter Release and Memory Consolidation

BIN1, a member of the BAR adaptor protein family, is a significant late-onset Alzheimer disease risk factor. Here, we investigate BIN1 function in the brain using conditional knockout (cKO) models. Loss of neuronal Bin1 expression results in the select impairment of spatial learning and memory. Exam...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: De Rossi, Pierre, Nomura, Toshihiro, Andrew, Robert J., Masse, Nicolas Y., Sampathkumar, Vandana, Musial, Timothy F., Sudwarts, Ari, Recupero, Aleksandra J., Le Metayer, Thomas, Hansen, Mitchell T., Shim, Ha-Na, Krause, Sofia V., Freedman, David J., Bindokas, Vytas P., Kasthuri, Narayanan, Nicholson, Daniel A., Contractor, Anis, Thinakaran, Gopal
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7146643/
https://ncbi.nlm.nih.gov/pubmed/32160554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.02.026
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados