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JNK/p66Shc/ITCH Signaling Pathway Mediates Angiotensin II-induced Ferritin Degradation and Labile Iron Pool Increase

Angiotensin II (Ang II) induces deleterious changes in cellular iron metabolism and increases the generation of reactive oxygen species. This leads to an impairment of neuronal and vascular function. However, the mechanism underpinning Ang II-induced changes in iron metabolism is not known. We hypot...

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Bibliografiske detaljer
Udgivet i:Nutrients
Main Authors: Borkowska, Andżelika, Popowska, Urszula, Spodnik, Jan, Herman-Antosiewicz, Anna, Woźniak, Michał, Antosiewicz, Jędrzej
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7146217/
https://ncbi.nlm.nih.gov/pubmed/32121405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu12030668
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