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JNK/p66Shc/ITCH Signaling Pathway Mediates Angiotensin II-induced Ferritin Degradation and Labile Iron Pool Increase

Angiotensin II (Ang II) induces deleterious changes in cellular iron metabolism and increases the generation of reactive oxygen species. This leads to an impairment of neuronal and vascular function. However, the mechanism underpinning Ang II-induced changes in iron metabolism is not known. We hypot...

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Publicado en:Nutrients
Main Authors: Borkowska, Andżelika, Popowska, Urszula, Spodnik, Jan, Herman-Antosiewicz, Anna, Woźniak, Michał, Antosiewicz, Jędrzej
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7146217/
https://ncbi.nlm.nih.gov/pubmed/32121405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu12030668
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