Histone lysine demethylase KDM4B regulates the alternative splicing of the androgen receptor in response to androgen deprivation

Alternative splicing is emerging as an oncogenic mechanism. In prostate cancer, generation of constitutively active forms of androgen receptor (AR) variants including AR-V7 plays an important role in progression of castration-resistant prostate cancer (CRPC). AR-V7 is generated by alternative splici...

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Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Duan, Lingling, Chen, Zhenhua, Lu, Jun, Liang, Yanping, Wang, Ming, Roggero, Carlos M, Zhang, Qing-Jun, Gao, Jason, Fang, Yong, Cao, Jiazheng, Lu, Jian, Zhao, Hongwei, Dang, Andrew, Pong, Rey-Chen, Hernandez, Elizabeth, Chang, Chun-Mien, Hoang, David T, Ahn, Jung-Mo, Xiao, Guanghua, Wang, Rui-tao, Yu, Kai-jiang, Kapur, Payal, Rizo, Josep, Hsieh, Jer-Tsong, Luo, Junhang, Liu, Zhi-Ping
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2019
Aiheet:
Gene regulation, Chromatin and Epigenetics
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7145715/
https://ncbi.nlm.nih.gov/pubmed/31647098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1004
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