Histone lysine demethylase KDM4B regulates the alternative splicing of the androgen receptor in response to androgen deprivation

Alternative splicing is emerging as an oncogenic mechanism. In prostate cancer, generation of constitutively active forms of androgen receptor (AR) variants including AR-V7 plays an important role in progression of castration-resistant prostate cancer (CRPC). AR-V7 is generated by alternative splici...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Duan, Lingling, Chen, Zhenhua, Lu, Jun, Liang, Yanping, Wang, Ming, Roggero, Carlos M, Zhang, Qing-Jun, Gao, Jason, Fang, Yong, Cao, Jiazheng, Lu, Jian, Zhao, Hongwei, Dang, Andrew, Pong, Rey-Chen, Hernandez, Elizabeth, Chang, Chun-Mien, Hoang, David T, Ahn, Jung-Mo, Xiao, Guanghua, Wang, Rui-tao, Yu, Kai-jiang, Kapur, Payal, Rizo, Josep, Hsieh, Jer-Tsong, Luo, Junhang, Liu, Zhi-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7145715/
https://ncbi.nlm.nih.gov/pubmed/31647098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1004
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