Histone lysine demethylase KDM4B regulates the alternative splicing of the androgen receptor in response to androgen deprivation

Alternative splicing is emerging as an oncogenic mechanism. In prostate cancer, generation of constitutively active forms of androgen receptor (AR) variants including AR-V7 plays an important role in progression of castration-resistant prostate cancer (CRPC). AR-V7 is generated by alternative splici...

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書誌詳細
出版年:Nucleic Acids Res
主要な著者: Duan, Lingling, Chen, Zhenhua, Lu, Jun, Liang, Yanping, Wang, Ming, Roggero, Carlos M, Zhang, Qing-Jun, Gao, Jason, Fang, Yong, Cao, Jiazheng, Lu, Jian, Zhao, Hongwei, Dang, Andrew, Pong, Rey-Chen, Hernandez, Elizabeth, Chang, Chun-Mien, Hoang, David T, Ahn, Jung-Mo, Xiao, Guanghua, Wang, Rui-tao, Yu, Kai-jiang, Kapur, Payal, Rizo, Josep, Hsieh, Jer-Tsong, Luo, Junhang, Liu, Zhi-Ping
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2019
主題:
Gene regulation, Chromatin and Epigenetics
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7145715/
https://ncbi.nlm.nih.gov/pubmed/31647098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1004
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