The lysine demethylase, KDM4B, is a key molecule in androgen receptor signalling and turnover

The androgen receptor (AR) is a key molecule involved in prostate cancer (PC) development and progression. Post-translational modification of the AR by co-regulator proteins can modulate its transcriptional activity. To identify which demethylases might be involved in AR regulation, an siRNA screen...

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Detalhes bibliográficos
Principais autores: Coffey, Kelly, Rogerson, Lynsey, Ryan-Munden, Claudia, Alkharaif, Dhuha, Stockley, Jacqueline, Heer, Rakesh, Sahadevan, Kanagasabai, O’Neill, Daniel, Jones, Dominic, Darby, Steven, Staller, Peter, Mantilla, Alejandra, Gaughan, Luke, Robson, Craig N.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632104/
https://ncbi.nlm.nih.gov/pubmed/23435229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt106
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