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Targeted DNA methylation of neurodegenerative disease genes via homology directed repair
DNA methyltransferases (DNMTs) are thought to be involved in the cellular response to DNA damage, thus linking DNA repair mechanisms with DNA methylation. In this study we present Homology Assisted Repair Dependent Epigenetic eNgineering (HARDEN), a novel method of targeted DNA methylation that util...
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| Publicat a: | Nucleic Acids Res |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7145628/ https://ncbi.nlm.nih.gov/pubmed/31680172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz979 |
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