Translation-dependent unwinding of stem–loops by UPF1 licenses Regnase-1 to degrade inflammatory mRNAs

Regnase-1-mediated mRNA decay (RMD), in which inflammatory mRNAs harboring specific stem–loop structures are degraded, is a critical part of proper immune homeostasis. Prior to initial translation, Regnase-1 associates with target stem–loops but does not carry out endoribonucleolytic cleavage. Singl...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Mino, Takashi, Iwai, Noriki, Endo, Masayuki, Inoue, Kentaro, Akaki, Kotaro, Hia, Fabian, Uehata, Takuya, Emura, Tomoko, Hidaka, Kumi, Suzuki, Yutaka, Standley, Daron M, Okada-Hatakeyama, Mariko, Ohno, Shigeo, Sugiyama, Hiroshi, Yamashita, Akio, Takeuchi, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
RNA and RNA-protein complexes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7145602/
https://ncbi.nlm.nih.gov/pubmed/31329944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz628
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados