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Phylogenetic debugging of a complete human biosynthetic pathway transplanted into yeast
Cross-species pathway transplantation enables insight into a biological process not possible through traditional approaches. We replaced the enzymes catalyzing the entire Saccharomyces cerevisiae adenine de novo biosynthesis pathway with the human pathway. While the ‘humanized’ yeast grew in the abs...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7145547/ https://ncbi.nlm.nih.gov/pubmed/31745563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1098 |
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