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Surface Stabilization and Dissolution Rate Improvement of Amorphous Compacts with Thin Polymer Coatings: Can We Have It All?

[Image: see text] The distinction between surface and bulk crystallization of amorphous pharmaceuticals, as well as the importance of surface crystallization for pharmaceutical performance, is becoming increasingly evident. An emerging strategy in stabilizing the amorphous drug form is to utilize th...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Pharm
Hauptverfasser: Novakovic, Dunja, Peltonen, Leena, Isomäki, Antti, Fraser-Miller, Sara J., Nielsen, Line Hagner, Laaksonen, Timo, Strachan, Clare J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2020
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7145361/
https://ncbi.nlm.nih.gov/pubmed/32027513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.9b01263
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