Dissolution Studies of Poorly Soluble Drug Nanosuspensions in Non-sink Conditions

Sink conditions used in dissolution tests lead to rapid dissolution rates for nanosuspensions, causing difficulties in discriminating dissolution profiles between different formulations. Here, non-sink conditions were studied for the dissolution testing of poorly water-soluble drug nanosuspensions....

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Main Authors: Liu, Peng, De Wulf, Odile, Laru, Johanna, Heikkilä, Teemu, van Veen, Bert, Kiesvaara, Juha, Hirvonen, Jouni, Peltonen, Leena, Laaksonen, Timo
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2013
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666001/
https://ncbi.nlm.nih.gov/pubmed/23615772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-013-9960-2
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