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Surface Stabilization and Dissolution Rate Improvement of Amorphous Compacts with Thin Polymer Coatings: Can We Have It All?

[Image: see text] The distinction between surface and bulk crystallization of amorphous pharmaceuticals, as well as the importance of surface crystallization for pharmaceutical performance, is becoming increasingly evident. An emerging strategy in stabilizing the amorphous drug form is to utilize th...

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Detalhes bibliográficos
Publicado no:Mol Pharm
Main Authors: Novakovic, Dunja, Peltonen, Leena, Isomäki, Antti, Fraser-Miller, Sara J., Nielsen, Line Hagner, Laaksonen, Timo, Strachan, Clare J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7145361/
https://ncbi.nlm.nih.gov/pubmed/32027513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.9b01263
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