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Role of Hepatitis B virus capsid phosphorylation in nucleocapsid disassembly and covalently closed circular DNA formation

Hepatitis B virus (HBV) delivers a partially double-stranded, relaxed circular (RC) DNA genome in complete virions to the host cell nucleus for conversion to the covalently closed circular (CCC) DNA, which establishes and sustains viral infection. An overlength pregenomic RNA (pgRNA) is then transcr...

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Vydáno v:PLoS Pathog
Hlavní autoři: Luo, Jun, Xi, Ji, Gao, Lu, Hu, Jianming
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7145273/
https://ncbi.nlm.nih.gov/pubmed/32226051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008459
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