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Involvement of Host ATR-CHK1 Pathway in Hepatitis B Virus Covalently Closed Circular DNA Formation

The covalently closed circular (CCC) DNA of hepatitis B virus (HBV) functions as the only viral transcriptional template capable of producing all viral RNA species and is essential to initiate and sustain viral replication. CCC DNA is converted from a relaxed circular (RC) DNA, in which neither of t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:mBio
Hauptverfasser: Luo, Jun, Luckenbaugh, Laurie, Hu, Hui, Yan, Zhipeng, Gao, Lu, Hu, Jianming
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029148/
https://ncbi.nlm.nih.gov/pubmed/32071277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.03423-19
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