DNA methylation and cis-regulation of gene expression by prostate cancer risk SNPs

Genome-wide association studies have identified more than 100 SNPs that increase the risk of prostate cancer (PrCa). We identify and compare expression quantitative trait loci (eQTLs) and CpG methylation quantitative trait loci (meQTLs) among 147 established PrCa risk SNPs in primary prostate tumors...

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Publicado en:PLoS Genet
Main Authors: Dai, James Y., Wang, Xiaoyu, Wang, Bo, Sun, Wei, Jordahl, Kristina M., Kolb, Suzanne, Nyame, Yaw A., Wright, Jonathan L., Ostrander, Elaine A., Feng, Ziding, Stanford, Janet L.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7145271/
https://ncbi.nlm.nih.gov/pubmed/32226005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008667
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